blood How I Treat

Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib
V. Koneti Rao, Sharon Webster, Virgil A. S. H. Dalm, Anna Šedivá, P. Martin van Hagen, Steven Holland, Sergio D. Rosenzweig, Andreas D. Christ, Birgitte Sloth, Maciej Cabanski, Aniket D. Joshi, Stefan de Buck, Julie Doucet, Danilo Guerini, Christoph Kalis, Ilona Pylvaenaeinen, Nicolas Soldermann, Anuj Kashyap, Gulbu Uzel, Michael J. Lenardo, Dhavalkumar D. Patel, Carrie L. Lucas, Christoph Burkhart
Nov 23, 2017
A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility
Erin C. Peckham-Gregory, Rikhia Chakraborty, Michael E. Scheurer, John W. Belmont, Harshal Abhyankar, Amel G. Sengal, Brooks P. Scull, Olive Eckstein, Daniel J. Zinn, Louisa Mayer, Albert Shih, Miriam Merad, D. Williams Parsons, Kenneth L. McClain, Philip J. Lupo, Carl E. Allen
Nov 16, 2017
Philadelphia chromosome–like acute lymphoblastic leukemia
Sarah K. Tasian, Mignon L. Loh, Stephen P. Hunger
Nov 09, 2017
How I treat patients with HIV-related hematological malignancies using hematopoietic cell transplantation
Joseph C. Alvarnas, John A. Zaia, Stephen J. Forman
Nov 02, 2017
CD207+CD1a+ cells circulate in pediatric patients with active Langerhans cell histiocytosis
Eugenio Antonio Carrera Silva, Wanda Nowak, Licina Tessone, Cinthia Mariel Olexen, Juan Manuel Ortiz Wilczyñski, Ivana Gisele Estecho, Graciela Elena, Andrea Emilse Errasti, Diego Alfredo Rosso
Oct 26, 2017
Oncogenetic mutations combined with MRD improve outcome prediction in pediatric T-Cell Acute Lymphoblastic Leukemia
Arnaud Petit, Amélie Trinquand, Sylvie Chevret, Paola Ballerini, Jean-Michel Cayuela, Nathalie Grardel, Aurore Touzart, Benoit Brethon, Hélène Lapillonne, Claudine Schmitt, Sandrine Thouvenin, Gerard Michel, Claude Preudhomme, Jean Soulier, Judith Landman-Parker, Guy Leverger, Elizabeth Macintyre, André Baruchel, Vahid Asnafi
Oct 19, 2017
Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis
Edyta Glogowska, Eve R. Schneider, Yelena Maksimova, Vincent P. Schulz, Kimberly Lezon-Geyda, John Wu, Kottayam Radhakrishnan, Siobán B. Keel, Donald Mahoney, Alison M. Freidmann, Rachel A. Altura, Elena O. Gracheva, Sviatoslav N. Bagriantsev, Theodosia A. Kalfa, Patrick G. Gallagher
Oct 19, 2017
Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia
Alan S. Wayne, Nirali N. Shah, Deepa Bhojwani, Lewis B. Silverman, James A. Whitlock, Maryalice Stetler-Stevenson, Weili Sun, Meina Liang, Jie Yang, Robert J. Kreitman, Mark C. Lanasa, Ira Pastan
Oct 05, 2017
Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype
Hye Sun Kuehn, Julie E. Niemela, Karthik Sreedhara, Jennifer L. Stoddard, Jennifer Grossman, Christian A. Wysocki, M. Teresa de la Morena, Mary Garofalo, Jingga Inlora, Michael P. Snyder, David B. Lewis, Constantine A. Stratakis, Thomas A. Fleisher, Sergio D. Rosenzweig
Sep 28, 2017
Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients
Paula Río, Susana Navarro, Guillermo Guenechea, Rebeca Sánchez-Domínguez, Maria Luisa Lamana, Rosa Yañez, Jose A. Casado, Parinda A. Mehta, Maria Roser Pujol, Jordi Surrallés, Sabine Charrier, Anne Galy, José C. Segovia, Cristina Díaz de Heredia, Julián Sevilla, Juan A. Bueren
Sep 28, 2017
How I treat myeloma with new agents
Philippe Moreau
Sep 28, 2017
Protocol II versus protocol III given twice during reinduction therapy in children with medium risk ALL
Franco Locatelli, Maria Grazia Valsecchi, Anja Möricke, Martin Zimmermann, Bernd Gruhn, Andrea Biondi, Andreas E. Kulozik, Daniela Silvestri, Nicole Bodmer, Maria Caterina Putti, Stefan Burdach, Concetta Micalizzi, Andrea Teigler-Schlegel, Jörg Ritter, Andrea Pession, Gunnar Cario, Stefan Bielack, Giuseppe Basso, Thomas Klingebiel, Luciana Vinti, Carmelo Rizzari, Andishe Attarbaschi, Nicola Santoro, Rosanna Parasole, Georg Mann, Leonid Karawajew, Oskar A. Haas, Valentino Conter, Martin Schrappe
Sep 22, 2017
New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia
Henrik Lilljebjörn, Thoas Fioretos
Sep 21, 2017
How I treat pediatric venous thromboembolism
Guy Young
Sep 21, 2017
How I monitor long-term and late effects after blood or marrow transplantation
Smita Bhatia, Saro H. Armenian, Wendy Landier
Sep 14, 2017
Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry
Takaya Moriyama, Yung-Li Yang, Rina Nishii, Hany Ariffin, Chengcheng Liu, Ting-Nien Lin, Wenjian Yang, Dong-Tsamn Lin, Chih-Hsiang Yu, Shirley Kham, Ching-Hon Pui, William E. Evans, Sima Jeha, Mary V. Relling, Allen Eng-Juh Yeoh, Jun J. Yang
Sep 07, 2017
How I treat first relapse of myeloma
Jean Luc Harousseau, Michel Attal
Aug 24, 2017
How I treat patients with aggressive lymphoma at high risk of CNS relapse
Collin K. Chin, Chan Yoon Cheah
Aug 17, 2017
Bone marrow failure unresponsive to bone marrow transplant is caused by mutations in thrombopoietin
Aaron Seo, Miri Ben-Harosh, Mehtap Sirin, Jerry Stein, Orly Dgany, Joseph Kaplelushnik, Manfred Hoenig, Ulrich Pannicke, Myriam Lorenz, Klaus Schwarz, Clemens Stockklausner, Tom Walsh, Suleyman Gulsuner, Ming K. Lee, Anoop Sendamarai, Marilyn Sanchez-Bonilla, Mary-Claire King, Holger Cario, Andreas E. Kulozik, Klaus-Michael Debatin, Ansgar Schulz, Hannah Tamary, Akiko Shimamura
Aug 17, 2017
Gemtuzumab ozogamicin in infants with AML: results from the Children’s Oncology Group trials AAML03P1 and AAML0531
Erin M. Guest, Richard Aplenc, Lillian Sung, Susana C. Raimondi, Betsy A. Hirsch, Todd A. Alonzo, Robert B. Gerbing, Yi-Cheng Jim Wang, Samir B. Kahwash, Amy Heerema-McKenney, Soheil Meshinchi, Alan S. Gamis
Aug 17, 2017
How I use laboratory monitoring of antiplatelet therapy
Alan D. Michelson, Deepak L. Bhatt
Aug 10, 2017
Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion
Franco Locatelli, Pietro Merli, Daria Pagliara, Giuseppina Li Pira, Michela Falco, Daniela Pende, Roberto Rondelli, Barbarella Lucarelli, Letizia Pomponia Brescia, Riccardo Masetti, Giuseppe Maria Milano, Valentina Bertaina, Mattia Algeri, Rita Maria Pinto, Luisa Strocchio, Raffaella Meazza, Lavinia Grapulin, Rupert Handgretinger, Alessandro Moretta, Alice Bertaina, Lorenzo Moretta
Aug 03, 2017
How I treat double-hit lymphoma
Jonathan W. Friedberg
Aug 03, 2017
Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation
Janine Schmidt, Joan Enric Ramis-Zaldivar, Ferran Nadeu, Blanca Gonzalez-Farre, Alba Navarro, Caoimhe Egan, Ivonne Aidee Montes-Mojarro, Teresa Marafioti, Jose Cabeçadas, Jon van der Walt, Stefan Dojcinov, Andreas Rosenwald, German Ott, Irina Bonzheim, Falko Fend, Elias Campo, Elaine S. Jaffe, Itziar Salaverria, Leticia Quintanilla-Martinez
Jul 20, 2017
Myeloid leukemia associated with Down syndrome
Caroline E. Talsma, Daniel F. Boyer
Jul 13, 2017